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Affiliation

Leiden University Medical Center

Country

The Netherlands

1. Current Status, Position

Dr Le Brun (PharmD, PhD, Assistant-professor) is currently a Hospital Pharmacist and Clinical Pharmacologist at LUMC Leiden. He is responsible for Quality assurance and he is Qualified Person and assistant-professor GMP at the Leiden University. 

2. Education

Dr Le Brun obtained his degree in pharmacy from the Groningen University in 1982. He started his career at the Dutch Laboratory of Pharmacists (LNA), department of the Royal Dutch Association of Pharmacists. The LNA supports Dutch local and hospital pharmacists with the preparation of medicines. From 1985 to 1988, he trained and worked as a hospital pharmacist in the Central Hospital Pharmacy of The Hague. He joined Merck Sharp & Dohme as production pharmacist from 1989 to 1992. GMP implementation, troubleshooting, training of personnel and product and process validation were his main responsibilities. In 1992, he was appointed director of production of the Central Hospital Pharmacy of The Hague where he worked until 2017. Since 2016, he is a member of the editorial board of the EJHP. Today he works at Leiden University medical centre where he is a qualified person and assistant-professor GMP. 

3. Research Area

Dr Le Brun obtained his PhD on the improvement and development of antibiotic inhalation for CF patients. The title of his thesis reads: “Optimization of antibiotic inhalation therapy in Cystic Fibrosis. Studies on nebulized tobramycin. Development of colistin dry powder inhaler systemb”. In 2001 he also received the innovation award of the Royal Dutch Society of Pharmacists for his research. He further specialised as clinical pharmacologist in 2002. To date he is involved in research on reconstitution and aseptic preparation. Dr Le Brun is one of the editors of Practical Pharmaceutics, a textbook about product care.

4. Conflict of interest: none

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