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PC2 – Navigating paediatric therapeutics: challenges in medicines and parenteral nutrition

Date:

12/03/2025 - 5:00 pm to 6:00 pm
13/03/2025 - 12:00 pm to 1:00 pm

Room:

Hall A3

Facilitator:

Stefanie Deuster

Abstract:

Link to EAHP Statements
Section 3 – Production and Compounding: Statements – 3.2
Section 4 – Clinical Pharmacy: Statements – 4.2, 4.4, 4.6
Section 5 – Patient Safety and Quality Assurance: Statements – 5.6

Abstract
Paediatric medicine presents unique challenges, particularly when it comes to drug therapy and nutrition in neonates. The use of drugs in children and neonates often requires off-label administration due to a lack of specific licensing for these age groups. Furthermore, establishing standardized guidelines for parenteral nutrition in neonates is an ongoing challenge, impacting their health and development. This seminar highlights two critical aspects of paediatric care: the complexities of drug therapy and the intricacies of parenteral nutrition in neonates.
In this seminar the first speaker will focus on the special needs of paediatric patients regarding drug pharmacokinetics, formulation, and dosing. The absence of paediatric-specific clinical trials for many drugs often leaves healthcare providers with the challenging task of adapting adult treatments for younger patients. This seminar will explore the challenges in paediatric drug dosing, the limitations of off-label drug use, and strategies to optimize medication safety and efficacy in children.
Neonates, especially those born prematurely, frequently require parenteral nutrition to support their growth and development. Yet, establishing a standardized approach to neonatal parenteral nutrition remains elusive. The second speaker will explain the complexities of neonatal nutritional requirements, the challenges of providing balanced parenteral nutrition, and the impact on neonatal outcomes, as well as current research and practices aiming to improve parenteral nutrition practice for neonates.

Learning objectives
After the session, the participant should be able to:

  • Describe strategies to optimise paediatric medication.
  • Evaluate the challenges and advantages of standardised parenteral nutrition.
  • Discuss the potential of manufacturing paediatric parenteral nutrition.

Educational need addressed
Hospital pharmacists need to know details on paediatric drug therapy as well as the challenges of neonate parenteral nutrition composition and manufacturing.

Keywords
Paediatrics, neonatology, nutrition, drug manufacturing, drug dosing.

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